Hydrogenated silicone oil is a silicone polymer composed of silicon-oxygen bonds and organic groups. In the pharmaceutical industry, it is widely used as a lubricant, coating agent, carrier, emulsifier and defoaming agent. This article will take an in-depth look at the applications and benefits of hydrogenated silicone oils in pharmaceuticals.
After reading this, if you still have questions about hydrogenated silicone oil, or want to find a professional manufacturer of hydrogenated silicone oil, please contact KBR to provide you with high-quality products and ordering information!
1. Lubricant
One of the main applications of hydrogenated silicone oils in pharmaceuticals is as a lubricant. When manufacturing tablets or capsule preparations, pharmaceutical powder may adhere to the mold walls, which affects product quality and yield. The use of hydrogenated silicone oil can effectively reduce the friction between powders, thereby improving fluidity and compressibility.
2. Coating agent
Another important application is as a coating agent. The taste and appearance of medicines are important, but some active ingredients may be sensitive to light, water or oxygen and require protection. As an inert compound, hydrogenated silicone oil can help protect drugs, enhance their stability and extend their shelf life. At the same time, it can also mask the bad taste and smell of medicines.
3. Carrier
Hydrosilicone oils are also used as carriers for medications, especially in topical treatments. It can help control the release rate of drugs and significantly improve their bioavailability. When hydrogenated silicone oil is combined with drugs, it can form particle-like structures that can help drugs enter cell membranes and tissues more easily.
4. Emulsifier
When manufacturing certain liquid formulations, emulsifiers are required to stabilize the mixture. Hydrogenated silicone oil is an excellent emulsifier that combines water and oil and prevents them from separating. This property makes it ideal for manufacturing emulsions, suspensions and creams.
5. Defoaming agent
Finally, hydrogenated silicone oil can also be used as a defoaming agent. When manufacturing some liquid preparations, bubbles may occur, which may affect the stability and quality of the preparation. Hydrogenated silicone oil can effectively eliminate bubbles to ensure the quality of the preparation.
In summary, hydrogenated silicone oils are widely used in pharmaceuticals and offer a variety of advantages, including enhanced drug stability, bioavailability, and formulation performance. It is a silicone compound well suited to the pharmaceutical industry, helping to create higher quality, more effective medicines.